Grey’s Anatomy
Grey ’s Anatomyis jazz for either killing some of its most popular characters or have them go , but not even destruction is a unequivocal terminal for these characters , as many of them have return at some gunpoint , either in dreams or hallucination . Some of these fiber returned for one special occasion whenGrey ’s Anatomycelebrated the Day of the Dead , and Meredith Grey ( Ellen Pompeo ) was jaw by some of her loved ones who have go past away . Grey ’s Anatomyhas gain over the hearts of the audience with its compounding of play and drollery , but the former has been taken too far sometimes .
Not only have Meredith and company grapple with the deaths of many , many patient over the course of 19 seasons , but they have also had to say goodbye to some of their closest Quaker and colleagues . As the confidential information of the serial , Meredith has seen some of her have intercourse one die , such as her best supporter George O’Malley ( T.R. Knight ) , her half - sister Lexie ( Chyler Leigh ) , and even her husband , Derek Shepherd ( Patrick Dempsey ) . However , Grey ’s Anatomyhas continue their legacies in different way and has n’t countenance Meredith and the rest forget them , and some of them even returned for the Day of the Dead in time of year 15 ’s installment “ Flowers Out of My Grave ” , and here ’s every deceased part who visited Meredith that Nox .
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6George O’Malley
George O’Malley was introduce inGrey ’s Anatomyseason 1 as an interne alongside Meredith and other darling fictitious character , as are Cristina Yang ( Sandra Oh ) and Alex Karev ( Justin Chambers ) . George became one of Meredith ’s closest friends , but unlike his friend , he struggle during his first year atSeattle Grace Hospital . George bomb his medical intern examination as he was distract by other problems ( mostly from his personal spirit ) , and even though he did become a resident , he made the sudden decision of joining the U.S. Army in Iraq . Richard Webber ( James Pickes Jr ) gave him his last day off so he could spend clip with his family , but on his way domicile , George jumped in front of a busbar to save a woman ’s life . George was add to the infirmary and was gravely blemish , to the point where he was unrecognisable .
George managed to hound “ 007 ” , a nicknamehis Quaker at the hospital had present him , on Meredith ’s hand , who quickly apprize the rest that their “ John Doe ” was George . Despite the squad ’s efforts , George ’s genius swelled during surgery and he was declared mastermind - bushed , so George O’Malley leftGrey ’s Anatomyin season 6 . George appear inGrey ’s Anatomy ’s Day of the Dead episode through archive footage , which is why he calculate very young .
5Lexie Grey
Lexie Grey was Meredith ’s younger paternal half - sister , and she made her debut inGrey ’s Anatomyseason 3 when she started her internship at Seattle Grace . Meredith was n’t welcome of Lexie even though the latter made an effort to get along with her , but with time , Meredith open up a bit more to her . alas , inGrey ’s Anatomyseason 8 , Meredith , Derek , Cristina , Mark Sloan ( Eric Dane ) , and Arizona Robbins ( Jessica Capshaw ) were on their way to assist the OR of conjoined twins at a hospital in Boise when their plane crashed . Lexie was crushed by a piece of the plane , hurt her pelvis , legs , and leave arm , and died moment after being find . Just like George , Lexie returned thanks to archive footage .
4Ellis Grey
Ellis Grey ( Kate Burton ) was Meredith and Maggie ’s ( Kelly McCreary ) mother and a universe - illustrious surgeon . Meredith and Ellis ’ kinship was complicated , as Ellis was more focused on her career and her affair with Richard Webber , and all that kept her away from her girl and even made her forget about her . Ellis was diagnose with Alzheimer ’s , which further complicated her relationship with Meredith , and she passed away inGrey ’s Anatomyseason 3 . Unlike the above characters , Burton return to play Ellis Greyin her very brief cameo in the serial publication ’ Day of the Dead episode , and she smiled as Meredith walked past her , making it a heartwarming second .
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3Mark Sloan
Mark Sloan was the Head of Plastic Surgery at Seatle Grace Mercy West Hospital , as well as Derek ’s in force friend and Lexie ’s on - and - off better half . Grey ’s Anatomymostly focused on Mark ’s love triangles and other personal problem , but that did n’t make his decease any less unspeakable . As mentioned above , Mark was also on the aeroplane when it crash , and though he seemed all right when he was get hold by his colleagues and friends , Cristina realized he had a cardiac tamponade ( fluid around the heart ) , but with Meredith ’s help , they drain the fluid . Unfortunately , Mark ’s wellness deteriorate , and inGrey ’s Anatomyseason 9premiere episode , he was on sprightliness supporting . As determined by his will , the motorcar were wrick off , and he break down with Derek and Callie Torres ( Sandra Ramirez ) by his side . Although he was n’t close to Meredith , Mark returned to check on her on the Day of the Dead , and just like with George and Lexie , this was achieved through archive footage .
2Doc
Meredith receive an additional special sojourn on the Day of the Dead : Doc , her dog . Izzie ( Katherine Heigl ) and Meredith take over Doc in season 2 , but the rest of her roomy did n’t care him around the house , so she gave him to Addison ( Kate Walsh ) and Derek . Meredith continued to visit Doc and would meet Derek in the ballpark to walk him together , but in time of year 2 , Doc got very sick and was diagnosed with off-white Crab . Not long after , Doc ’s consideration worsen and he was put to sleep , and he died withMeredith and Derekby his side . Doc returned to jaw Meredith on the Day of the Dead in a surprise but heartwarming visual aspect .
1Derek Shepherd
Last but not least , Derek Shepherd visit his wife on the Day of the Dead . Derek and Meredith wereGrey ’s Anatomy ’s independent yoke during the show ’s first 11 seasons , though their relationship was a rollercoaster . After a lot of trouble in their marriage ceremony and Derek moving to Washington D.C. for work , Derek decided to move back to Seattle to be with his family , but he had to go back to D.C. to resign . On his manner there , he got into a car accident and was deal to Grey Sloan Memorial Hospital , but even though the team did their best , there were a lot of complications andDerek could n’t be saved . Meredith resolve to remove him from life support , and so Derek Shepherd passed away inGrey ’s Anatomyseason 11 . Patrick Dempsey did n’t devolve to dart his cameo show in the Day of the all in sequence , so archive footage was used .
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